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Somaesthetic evoked potentials (SEPs) have been recorded on the parietal scalp of 375 normal and awake children to brief electrical stimulation (0.5 msec) applied to the contralateral median nerve at the wrist. Each SEP was obtained by summation of the responses to 150 stimuli delivered at a frequency of 1/sec. The population studied has been divided in… (More)
The locked in syndrome seldom occurs in children, is rarely due to trauma and only in exceptional cases has a favourable outcome. The case reported below is unusual in all these respects, and its evolution might be an example of successful axonal regeneration in the central nervous system.
An electromyographic study was performed in 50 cases of severe infantile spinal muscular atrophy (type I). 164 muscles and 93 nerves (ulnar and posterior tibialis) were tested. The thresholds of stimulation of the motor nerves were increased. Motor action potential was absent in 30% of the investigated nerves, motor nerve conduction velocity was slow in… (More)
Alterations of the functional properties of the cerebellar parallel fibers have been investigated in scrapie mice by recording the compound action potential elicited by the superficial stimulation of the cerebellum. As soon as the 12th week following intracerebral inoculation, i.e. during the silent incubation period, there is a clear decrease of the… (More)
Thirteen children, aged 10 months to 20 years, presenting with chronic cholestasis from the first month of life and with low serum levels of vitamins A and/or E, have been investigated for neurological and ophthalmological symptoms. Clinical findings consisted of 4 types: peripheral neuropathy; cerebellar dysfunction; abnormalities of eye movement, and… (More)
The results of somesthetic evoked response (SER) and electroencephalogram (EEG) records in 43 children with hemiplegic cerebral palsy have been compared. In all children there was a positive correlation between the SER changes and the affected side of the body. In 12 children the SER of the "damaged" hemisphere disappeared; in 31 children it was less than… (More)
Treatment of plasma membrane isolated from murine plasmocytoma MOPC 173 with an EDTA-containing buffer resulted in a 300-fold increase in sensitivity of (Na+ + K+)-stimulated Mg2+-ATPase to ouabain. This phenomenon was associated with the solubilization by EDTA of phospholipid free proteins (approx. 30 000-34 000 daltons) from the cytoplasmic face of the… (More)