Pierre-Louis Couturier

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Decreasing organ quality is prompting research toward new methods to alleviate ischemia reperfusion injury (IRI). Oxidative stress and nuclear factor kappa beta (NF-κB) activation are well-described elements of IRI. We added cyclodextrin-complexed curcumin (CDC), a potent antioxidant and NF-κB inhibitor, to University of Wisconsin (UW) solution (Belzer's(More)
We describe a 55-year-old woman with extensive digestive resection and recurrent depressive disorder resistant to oral clomipramine tablets but not to an oral solution of amitriptyline. In the light of this case report, the potential mechanisms of drug resistance after digestive resection are discussed, including the importance of drug monitoring.
OBJECTIVES The first year of medical school in France (PCEM 1) is very competitive, as the 2004-2005 success rate at the Paris V university was below 20%. Future medical students, as well as the other actors of medical education, are therefore willing to know what are the factors for success in PCEM 1 as well as whether or not the widespread complementary(More)
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