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Colistin pharmacokinetics (PK) was investigated in young healthy volunteers after a 1-h infusion of 80 mg (1 million international units (MIU)) of the prodrug colistin methanesulfonate (CMS).… (More)
Type 2 diabetes (T2D) is an important risk factor for atrialﬁbrillation (AF) and cardiovascular diseases [1,2]. While diabeticnephropathy is a well-established risk factor for cardiovascularoutcomes… (More)
Aim: We tested whether inflammation and oxidative stress biomarkers may predict the risk of peripheral arterial disease (PAD) in the SURDIAGENE (SURvie, DIAbete de type 2 et GENEtique) type 2… (More)
n engl j med 375;24 nejm.org December 15, 2016 per severe disability is a better outcome than a modified Rankin score of 4 (on a scale from 0 [no symptoms] to 6 [death]), the threshold that has… (More)
Clinical trials in patients with type 2 diabetes (T2D) showed that the incidence of lower limb amputations (LLA) was doubled in patients in canagliflozin arm compared with placebo. Whether… (More)
Introduction Il existe un lien entre le sexe masculin et le risque de nephro-pathie associee au diabete de type 2 (DT2), suggerant une implication des steroides sexuels. Nous avons cherche a… (More)