Pierre-Emmanuel Gros

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Biologists are leading current research on genome characterization (sequencing, alignment, transcription), providing a huge quantity of raw data about many genome organisms. Extracting knowledge from this raw data is an important process for biologists, using usually data mining approaches. However, it is difficult to deals with these genomic information(More)
In this paper, we address the potential offered by Virtual Reality and scientific simulation for 3D modeling and immersive visualization of huge genomic sequences. Advanced work on 3D data modeling and structuring is proposed. In Bioinformatics, DNA sequences are often represented within linear format. However, they also have a three-dimensional structure(More)
In this paper, we address the potential offered by Virtual Reality for 3D modeling and immersive visualization of large genomic sequences. The representation of the 3D structure of DNA allows biologists to observe and analyze genomes in an interactive way at different levels. We developed a powerful software platform that provides a new point of view for(More)
Many databases and software tools are currently available for accessing genomic data. In general, each tool uses a different type of data in exchange protocols, and usually they offer specific services. The presented system approach, named GenoMEDIA, addresses the problem of integrating these heterogeneous databases and software utilities within a generic(More)
Huge volumes of bioinformatics data are emerging from sequencing efforts, gene expression assays, X-ray crystallography of proteins, and many other activities. High-throughput experimental methods produce masses of data, so that the whole of biology has changed from a data-light science into a data-driven science. Currently there are a lot of databases and(More)
Many databases and software tools are available for biologists in order to have access to genomic information. In a SQL manner, our information system GenoMEDIA addresses the problem of integrating heterogeneous data-bases and software utilities within a generic distributed platform. Lysa increases the GenoMEDIA SQL interface by adding an interactive(More)
Biological databases have become increasingly important distributed resources in this field. These databases contain a mix of data types, including sequence data, structured data such as molecular weights or GC content, and annotations in terms of controlled vocabularies and, increasingly, ontology such as the gene ontology, as well as free text data in(More)
Genomic information shows some characteristics that make them very difficult to interpret and to exploit. Such data constitute an important factual resource (GenBank, SwissProt, GeneOntology, or Decrypthon…), are heterogeneous, huge in quantity, and are geographically distributed. They are also recorded in structured or semi-structured formats within public(More)
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