Enantioselective modular synthesis of 2,4-disubstituted cyclopentenones by iridium-catalyzed allylic alkylation.
Iridium-catalysed asymmetric allylic substitutions.
- G. Helmchen, Axel Dahnz, Pierre Duebon, M. Schelwies, R. Weihofen
- Chemistry, BiologyChemical Communications
- 9 February 2007
Applications, based on combinations of the allylic substitution and ring closing metathesis, indicate considerable potential of the method for the synthesis of biologically active compounds.
Highly enantioselective syntheses of heterocycles via intramolecular Ir-catalyzed allylic amination and etherification.
- Carolin Welter, Axel Dahnz, B. Brunner, S. Streiff, Pierre Duebon, G. Helmchen
- ChemistryOrganic Letters
- 26 February 2005
Enantioselective Ir-catalyzed intramolecular allylic aminations and etherifications are described and new phosphorus amidites as well as improved conditions for intermolecular aminations are reported.
Amino acid and peptide bioconjugates of copper(II) and zinc(II) complexes with a modified N,N-bis(2-picolyl)amine ligand.
- S. Kirin, Pierre Duebon, T. Weyhermüller, E. Bill, N. Metzler‐Nolte
- Chemistry, BiologyInorganic Chemistry
- 25 July 2005
Metal-peptide conjugates like 8(M) as artificial metallochaperones are suggested because they have the potential to deliver metal ions to specific compartments in the cell as determined by the peptide moieties.
Preparation of 2,4-disubstituted cyclopentenones by enantioselective iridium-catalyzed allylic alkylation: synthesis of 2'-methylcarbovir and TEI-9826.
A broadly applicable synthesis of chiral 2- or 2,4-substituted cyclopent-2-enones has been developed by combining asymmetric iridium-catalyzed allylic alkylation reactions and ruthenium-catalyzed…
Enantioselective Synthesesof 2-Substituted Pyrrolidines from Allylamines by Domino Hydroformylation-Condensation:Short Syntheses of (S)-Nicotine and theAlkaloid 225C
Short routes to chiral 2-substituted pyrrolidines based on rhodium-catalyzed hydroformylations of allylamines and their N-alkyl and N-acyl derivatives, which were prepared by asymmetric allylic…
Ir-Catalyzed Allylic Amination and Etherification
Significance: This system allows for highly stereoselective intramolecular allylic aminations and etherifications as well as intermolecular allylic amination followed by intramolecular cyclization…
On the Value of Patents in Lean IP Management
This article highlights under which unique conditions value can be assigned to patents by the concept of Lean IP Management. In general, a patent can be regarded as a positive asset when it covers…
Polyamide molding compositions with enhanced flame retardation of glass fiber
Masa de moldeo de poliamida con la siguiente composicion, (A) del 25 al 90 % en peso de al menos una poliamida, (B) del 5 al 60 % en peso de fibras de vidrio, ascendiendo la media aritmetica de su…
Glass fiber reinforced flame-retardant polyamidstøbemasser