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Mechanical activities developed by cells play a significant role in the embryogenesis, development, and physiopathology of pluricellular organisms. A technique is described to measure in vitro the traction force developed by cells seeded into a three-dimensional polymeric collagen lattice. It is based on the use of strain gauges generating an electrical(More)
When cultivated within a matrix made of reconstituted collagen fibers, fibroblasts derived from skin, tendon, vena cava, and aorta of a normal (N) calf retract the lattice. This effect progresses with time and is related to the density of the cells included in the lattice. Under similar conditions, fibroblasts derived from the skin of 2 dermatosparactic (D)(More)
OBJECTIVES To assess means and constraints of preconception care implementation. METHODS Three strategies were applied to promote preconception health: organisation of a campaign, production of guidelines, and implementation of a preconception pilot clinic. Three surveys investigated the knowledge and practices of women before and after the campaign, and(More)
A group of women with unknown last menstrual period was studied representing 16% of a total of 22 404 pregnant women recorded using a common perinatal form. Unknown menstrual period is associated with high rates of low birth weight and with low socioeconomic and sociodemographic status. Such characteristics are also associated with a high rate of preterm(More)
Serum prolactin has been measured in blood samples collected daily during 51 menstrual cycles using an homologous human radioimmunoassay for 17 cycles and an homologous ovine radioimmunoassay for 34 cycles. There was a progressive and significant increase in serum prolactin during the late follicular phase, with a maximal value concomitant to the LH peak.(More)
Globally, maternal and child health faces diverse challenges depending on the status of the development of the country. Some countries have introduced or explored preconception care for various reasons. Falling birth rates and increasing knowledge about risk factors for adverse pregnancy outcomes led to the introduction of preconception care in Hong Kong in(More)
Serum progesterone and prolactin were measured in single blood samples collected from 176 mothers during a lactation period of 2 years and from fifty-six non-lactating, non-pregnant and regularly menstruating women from the Kivu region (Zaïre). On the basis of serum progesterone levels, evidence of corpus luteum activity was obtained in 61% of non-lactating(More)
Serum prolactin, LH, FSH, and estradiol were measured in single blood samples collected from 465 nursing mothers in Central Africa (Kivu, Zaïre) during the first 2 postpartum years. Lactating mothers were hyperprolactinemic during 15 to 18 postpartum months. Both serum prolactin and FSH were higher in amenorrheic than in menstruating nursing mothers; the(More)
We present a novel approach for improving the management of patients with pigmented neoplasms including malignant melanomas and dysplastic nevi. A cohort of 215 dysplastic nevi and malignant melanomas was studied by cyanoacrylate skin surface stripping (CSSS) and conventional histology. Presence of atypical melanocytes was found in the stratum corneum in(More)
The normal range of serum progesterone (measured by radioimmunoassay) and urinary pregnanediol during the menstrual cycle was determined in 86 patients (33 control and 53 with menstrual disorders or sterility) and the values were found to show a logarithmic distribution. The overall correlation between serum progesterone and urinary pregnanediol(More)