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Nowadays, object-oriented meta-languages such as MOF (Meta-Object Facility) are increasingly used to specify domain-specific languages in the model-driven engineering community. However, these meta-languages focus on structural specifications and have no built-in support for specifications of operational semantics. In this paper we explore the idea of using(More)
Domain specific languages for model transformation have recently generated significant interest in the model-driven engineering community. The adopted QVT specification has normalized some scheme of model transformation language; however several different model transformation language paradigms are likely to co-exist in the near future, ranging from(More)
This paper discusses platform independent Web application modeling and development in the context of model-driven engineering. A specific metamodel (and associated notation) is introduced and motivated for the model-ing of dynamic Web specific concerns. Web applications are represented via three independent but related models (business , hypertext and(More)
Metamodeling is raising more and more interest in the field of language engineering. While this approach is now well understood for defining abstract syntaxes, formally defining concrete syntaxes with metamodels is still a challenge. Concrete syntaxes are traditionally expressed with rules, conforming to EBNF-like grammars, which can be processed by(More)
Model transformation is a core mechanism for model-driven engineering (MDE). Writing complex model transformations is error-prone, and efficient testing techniques are required as for any complex program development. Testing a model transformation is typically performed by checking the results of the transformation applied to a set of input models. While it(More)
Model-driven engineering and model-based approaches have permeated all branches of software engineering; to the point that it seems that we are using models, as Molière's Monsieur Jourdain was using prose, without knowing it. At the heart of modeling, there is a relation that we establish to represent something by something else. In this paper we review(More)
BACKGROUND We report that a lasting deficit in the hedonic character of olfactory and gustatory perception can be observed in bilateral dorsomedial and intralaminar thalamic lesions. CASE DESCRIPTION A 68-year-old patient abruptly presented with vigilance disorders associated with a reduction of olfactory and gustatory perceptions. A severe drop in(More)
This paper discusses platform independent web application modeling in the context of model-driven engineering. A specific metamodel (and associated notation), companion of the UML metamodel, is introduced and motivated for the modeling of dynamic web specific concerns. Web applications are represented in three independent aspects (business, hypertext and(More)
This article describes the experiences of two independent start-up companies that were created in the white-heat of the early days of model-based engineering. Each company aimed to revolutionise software development by raising the level of abstraction through modelling. The article describes the context, technical innovations, business experiences, demise(More)
BACKGROUND Neonates from isoimmunized pregnancies have increased morbidity from neonatal jaundice. The increased bilirubin from haemolysis often needs phototherapy, exchange transfusion or both after birth. Various trials in pregnant women who were not isoimmunized but had other risk factors for neonatal jaundice have shown a reduction in need for(More)