Piermichele Paolillo

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The late-preterm infants are a group of premature steadily increasing, different from term infants as immature in terms of respiratory, metabolic, neurological, and immunological features. They may present at birth and during the first week of life various diseases and brain lesions echographically evident. We analyzed the neonatal outcomes of 417(More)
OBJECTIVES Few data exist about patient-triggered ventilation techniques in neonatal critical care. Our aim was to compare pressure-limited synchronised intermittent positive pressure (or assist/control) ventilation (sIPPV) in the classical time-cycled (TC-sIPPV) mode against flow-cycled (FC-sIPPV) modality. In this latter, typical sIPPV full respiratory(More)
OBJECTIVE Lutein is an antioxidant carotenoid exerting a key role in eye health, but no reference curve in the perinatal period is available. DESIGN AND METHODS We conducted a prospective study on the distribution of lutein and its metabolite 3'-oxolutein in arterial cord blood of preterm (n=40) and term (n=76) newborns according to gestational age, sex(More)
Respiratory Syncytial Virus infections are one of the leading causes of severe respiratory diseases that require hospitalization and, in some cases, intensive care. Once resolved, there may be respiratory sequelae of varying severity. The lack of effective treatments for bronchiolitis and the lack of vaccines for RSV accentuate the role of prevention in(More)
BACKGROUND Early discharge of healthy late preterm and full term newborn infants has become common practice because of the current social and economic necessities. Severe jaundice, and even kernicterus, has developed in some term infants discharged early. This study was designed to elaborate a percentile-based hour specific total serum bilirubin (TSB)(More)
UNLABELLED Preterm newborns may be discharged when clinical conditions are stable and maturity of physiological functions has been gained, but no precise indications on weight and GA to be reached before discharge are available. In our NICU we have observed in the last five years 234 newborns < 32 weeks of GA; we have decided to transfer from incubators at(More)
BACKGROUND Late preterm (LP) are at higher risk than term infants to develop infections due to their more immature immune system. Little data about the risks and incidence of infection and sepsis in LP are present in literature. AIMS To evaluate treated infection rates and risk factors for infection in moderate and late preterm infants (gestational age =(More)
OBJECTIVE To measure the red cell distribution width (RDW) ranges at birth and to evaluate potential association with typical neonatal diseases: patent of the ductus arteriousus (PDA), bronchopulmonary dysplasia (BPD), and late-onset sepsis (LOS) mortality. METHODS Forty-six full-term, 41 preterm, and 35 intrauterine growth restricted (IUGR) infants(More)
Materials and methods The database of the Neonatal Emergency TransportService in Lazio Region andall newborns transported within May 2009-December 2012 wereanalyzed (N=2,331). A multinomial logistic regression model was used to study the association between stabilization time and improvement and deterioration in TRIPS score in reference to no change,(More)
AIM Despite advances in perinatal management, there is a flat trend in incidences of respiratory distress syndrome (RDS) and bronchopulmonary dysplasia (BPD) in preterm infants. The main feature of BPD development in preterm infants is an imbalance between increased exposure to free radicals and inadequate antioxidant defences. We investigated the(More)