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  • Pier Francesca Porceddu, Ismail Ogunbayode Ishola, Liliana Contu, Micaela Morelli
  • Medicine, Biology
  • Neurotoxicity Research
  • 2016 (First Publication: 1 July 2016)
  • Metformin, a well-known antidiabetic drug, has recently been proposed to promote neurogenesis and to have a neuroprotective effect on the neurodegenerative processes induced by the dopaminergicContinue Reading
  • Giulia Costa, Pier Francesca Porceddu, +6 authors Micaela Morelli
  • Biology, Medicine
  • International journal of molecular sciences
  • 2019 (First Publication: 28 March 2019)
  • Ras homolog enriched in striatum (Rhes) is a protein that exerts important physiological functions and modulates psychostimulant drug effects. On this basis, the object of this study was to assessContinue Reading
  • Mária Baranyi, Pier Francesca Porceddu, +12 authors Beáta Sperlágh
  • Biology, Medicine
  • Molecular Neurodegeneration
  • 2015 (First Publication: 1 December 2016)
  • BackgroundMitochondrial dysfunction, oxidative stress and their interplay are core pathological features of Parkinson’s disease. In dopaminergic neurons, monoamines and their metabolites provide anContinue Reading
  • Lucia Frau, Nicola Simola, Pier Francesca Porceddu, Micaela Morelli
  • Biology, Medicine
  • Neurotoxicology
  • 2016 (First Publication: 1 September 2016)
  • 3,4-methylenedyoxymethamphetamine (MDMA or "ecstasy"), a recreational drug of abuse, can induce glia activation and dopaminergic neurotoxicity. Since MDMA is often consumed in crowded environmentsContinue Reading