Pier Emilio Ladetto

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The aim of the study was to evaluate whether the combination of ketanserin with captopril exerts an additive antihypertensive effect, as compared with single drug treatment. Twelve patients with uncomplicated moderate essential hypertension received, according to a randomized, double-blind, crossover design, ketanserin (40 mg twice daily), captopril (50 mg(More)
A radioimmunologic assay method was employed for assessing the hematic and urinary levels of beta methyl-digoxin in patients with various degrees of renal function, evaluated by creatinine clearance test. Significantly elevated hematic values and reduced clearance rates of MD were observed only in patients whose creatinine clearance values were below 50(More)
Creatinine clearance was evaluated in individuals with varying degrees of renal function following the administration of beta-methyl-digoxin. From the results of the experiment it can be deduced that significantly increased hematic values and renal clearance values definitely lower than normal appear only in patients of a creatinine clearance of less than(More)
An assessment was made of the ability of an ergometric test to detect coronary patients in evaluating the reliability of the effort test, which is mainly important when it gives the percentage of coronary patients that can be discovered at an early stage during screening. The concept of sensitivity and specificity is analysed with respect to the diagnostic(More)