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BACKGROUND Contrast-induced nephropathy is a serious complication of diagnostic and interventional procedures. PURPOSE To evaluate the nephrotoxicity of high- and low-osmolar contrast media (HOCM, LOCM) on kidneys in Sprague-Dawley rats. Telmisartan was administered to confirm its protective role against nephrotoxicity induced by contrast media. (More)
OBJECTIVE The objective of this study is to evaluate the effect and mechanism of aging on iodinated-contrast-media-induced nephropathy in male rats. METHODS Twenty-four healthy male rats were initially divided into 12-month-old and 24-month-old age groups (adult and older age groups, respectively; n = 12/group); subsequently, each age group was randomly(More)
Oestrus and ovulation were induced in a group of 19 yearling dairy goats which had been maintained for 70 days on a 19 h/day photoperiod regimen. Six yearling females, raised under natural photoperiod, served as controls. An intact, light-treated male was introduced to each group 42 days after termination of the artificial lighting. Behavioural, endocrine(More)
Tension-type headache (TTH) is the most prevalent type of primary headache. Many studies have shown that the pathogenesis of primary headache is associated with fine structural or functional changes. However, these studies were mainly based on migraine. The present study aimed to investigate whether TTH patients show functional disturbances compared with(More)
OBJECTIVE Cutaneous allodynia (CA) is a characteristic of central sensitization, predicting migraine progression, and poor response to therapy. The present study aimed to find out the cerebral functional alterations related to the establishment of central sensitization in migraineurs using functional magnetic resonance imaging (fMRI). DESIGN The(More)
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