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Diclofenac sodium (Voltaren) is a non-steroid anti-inflammatory agent of a new chemical structure, which is animal experiments shows a high degree of anti inflammatory, analgesic, and antipyretic activity in various pharmacological models. It inhibits prostaglandin biosynthesis in vitro and in vivo, and this inhibitory effect at least partly explains the(More)
6. Tritthart, H., Fleckenstein, B., Fleekenstein, A., Krause, H.: Frequenzabhgngige Einflfisse yon antiarrhythmiseh-wirksamen Substanzen auf die Aufstrichsgesehwindigkeit des Aktionspotentials (Versuche an isolierten Meersehweinehenpapillarmuskeln). Pflfigers Arch. ges. Physiol. 800, 52 (1968). 7. -Fleckenstein, A., Fleckenstein, B., Herbst, A., Krause, H.(More)
The cardiovascular effects of compound CIBA 34,276-Ba and imipramine were compared. In the conscious dog, intravenous infusion or oral administration of compond CIBA 34,276-Ba had only a slight effect on blood pressure and heart rate, whereas the intravenous administration of imipramine gave rise to clearcut tachycardia and did not influence blood pressure.(More)
1. In the intact or nephrectomized rat, the pressor responses to synthetic angiotensin-II-amide, beta-angiotensin-II and native "rat angiotensin" could be inhibited by intravenous injection of rabbit serum containing antibodies against synthetic angiotensin-II-amide.2. The pressor responses to vasopressin or noradrenaline were not influenced by(More)