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INTRODUCTION In this study, we used a newly developed method for measuring passive length-tension relations of a single human muscle in vivo to quantify changes in the mechanical properties of the human gastrocnemius after eccentric exercise. METHODS Twelve subjects performed eccentric exercise on the right leg for 1 h by walking backward downhill on a(More)
The study of muscle growth and muscle length adaptations requires measurement of passive length-tension properties of individual muscles, but until now such measurements have only been made in animal muscles. We describe a new method for measuring passive length-tension properties of human gastrocnemius muscles in vivo. Passive ankle torque and ankle angle(More)
BACKGROUND Falls are common in people with multiple sclerosis (PwMS). Previous studies have generally included small samples and had varied methods. OBJECTIVES The objectives of this paper are to compile fall rates across a broad range of ages and disease severity and to definitively assess the extent to which MS-associated and demographic factors(More)
OBJECTIVE To evaluate psychometric properties of 16-item and 7-item Falls Efficacy Scale-International (FES-I) in people with multiple sclerosis (MS). DESIGN Validation and prospective cohort study. SETTING People with MS living in metropolitan areas. PARTICIPANTS Community-dwelling people with MS (N=169; aged 21-73y) who were referred to Multiple(More)
Comprehensive characterization of stress relaxation in musculotendinous structures is needed to create robust models of viscoelastic behavior. The commonly used quasi-linear viscoelastic (QLV) theory requires that the relaxation response be independent of tissue strain (length). This study aims to characterize stress relaxation in the musculotendinous and(More)
BACKGROUND Stepping impairments increase fall risk in people with MS. No studies have evaluated step training for reducing fall risk in this population. OBJECTIVES To determine if step training can improve physical and neuropsychological measures associated with falls in MS. METHODS 50 PwMS with moderate disability participated in a randomized(More)
MOST PHYSIOLOGY TEXTS imply that the mechanism by which force is transmitted from sarcomeres to muscle insertions is simple: when skeletal muscles contract, cross-bridge forces are transmitted along myofibrils, through the sarcolemma and extracellular matrix to tendons and, ultimately, bones. At each level of organization, myofibrils, muscle fibers, and(More)
The plantarflexors of the lower limb are often assumed to act as independent actuators, but the validity of this assumption is the subject of considerable debate. This study aims to determine the degree to which passive changes in gastrocnemius muscle length, induced by knee motion, affect the tension in the adjacent soleus muscle. A second aim is to(More)