Phillippe P Lefebvre

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Limited regenerative response occurs in mammalian vestibular epithelia, although vestibular hair cell regeneration in mammals has been demonstrated under a variety of experimental conditions. Beta-catenin is known to play an important role in both cell-cell adhesion and signal transduction associated with cell proliferation. This study evaluated cell(More)
Severe damage by acoustic overstimulation or ototoxins induces inner ear hair cell loss, resulting in permanent hearing loss and balance disorders because hair cell regeneration scarcely occurs in the inner ear sensory organs of mammals. In this study, to evaluate the possibilities of cell transplantation therapy for damaged inner ear sensory organs,(More)
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