Phillip E. Pace

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Many radar and communications applications require detection and estimation of signal information across an extremely wide radio frequency (RF) bandwidth. In practice, however, direct digitization of this broadband RF environment is problematic. Physical limitations in analog-to-digital converter (ADC) technology restrict the total bandwidth that can be(More)
Phosphorylation provides an important mechanism by which transcription factor activity is regulated. Estrogen receptor alpha (ERalpha) is phosphorylated on multiple sites, and stimulation of a number of growth factor receptors and/or protein kinases leads to ligand-independent and/or synergistic increase in transcriptional activation by ERalpha in the(More)
A variant form of the human oestrogen receptor (ER) mRNA lacking sequences encoded within exon 5 has been described (Fuqua SAW, Fitzgerald SD, Chamness GC, Tandon AK, McDonnell DP, Nawaz Z, O'Malloy BW, McGuire WL 1991, Cancer Res 51: 105-109). We have examined the expression of the exon 5-deleted ER (HE delta5) mRNA variant in breast biopsies using reverse(More)
Abstruct-High performance analog-to-digital converters (ADC's) employ a parallel configuration of analog folding circuits to symmetrically fold the input signal prior to quantization by high speed comparators (analog preprocessing). This paper identifies a new preprocessing approach that can be easily incorporated into the established techniques to provide(More)