Philippe Vuistiner

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The purpose of this study was to estimate the energy cost of linear (EC) and vertical displacement (ECvert), mechanical efficiency and main stride parameters during simulated ski mountaineering at different speeds and gradients, to identify an optimal speed and gradient that maximizes performance. 12 subjects roller skied on a treadmill at three different(More)
BACKGROUND Workers with persistent disabilities after orthopaedic trauma may need occupational rehabilitation. Despite various risk profiles for non-return-to-work (non-RTW), there is no available predictive model. Moreover, injured workers may have various origins (immigrant workers), which may either affect their return to work or their eligibility for(More)
BACKGROUND Although the relationship between serum uric acid (SUA) and adiposity is well established, the direction of the causality is still unclear in the presence of conflicting evidences. We used a bidirectional Mendelian randomization approach to explore the nature and direction of causality between SUA and adiposity in a population-based study of(More)
OBJECTIVE We investigated factors associated with masked and white-coat hypertension in a Swiss population-based sample. METHODS The Swiss Kidney Project on Genes in Hypertension is a family-based cross-sectional study. Office and 24-hour ambulatory blood pressure were measured using validated devices. Masked hypertension was defined as office blood(More)
BACKGROUND Urinary creatinine excretion is used as a marker of completeness of timed urine collections, which are a keystone of several metabolic evaluations in clinical investigations and epidemiological surveys. METHODS We used data from two independent Swiss cross-sectional population-based studies with standardised 24-hour urinary collection and(More)
The aim of this study is to describe the effects of speed and gradient during uphill ski mountaineering on energy expenditure, to relate any changes to changes in stride characteristics, and to determine an optimal gradient and speed allowing minimization of energy expenditure. 11 subjects were tested on snowy trails using their mountaineering skis (fitted(More)
BACKGROUND Validated clinician outcome scores are considered less associated with psychosocial factors than patient-reported outcome measurements (PROMs). This belief may lead to misconceptions if both instruments are related to similar factors. QUESTIONS We asked: In patients with chronic shoulder pain, what biopsychosocial factors are associated (1)(More)
BACKGROUND We elaborated a model that predicts the centiles of the 25(OH)D distribution taking into account seasonal variation. METHODS Data from two Swiss population-based studies were used to generate (CoLaus) and validate (Bus Santé) the model. Serum 25(OH)D was measured by ultra high pressure LC-MS/MS and immunoassay. Linear regression models on(More)
BACKGROUND In a simulation based on a pharmacokinetic model we demonstrated that increasing the erythropoiesis stimulating agents (ESAs) half-life or shortening their administration interval decreases hemoglobin variability. The benefit of reducing the administration interval was however lessened by the variability induced by more frequent dosage(More)
The method of instrumental variable (referred to as Mendelian randomization when the instrument is a genetic variant) has been initially developed to infer on a causal effect of a risk factor on some outcome of interest in a linear model. Adapting this method to nonlinear models, however, is known to be problematic. In this paper, we consider the simple(More)
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