Philippe Vivet

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AIM The pharmacologic effects of sodium oxybate (SO) have a number of similarities with those of alcohol. This study evaluated the pharmacodynamic interaction of SMO.IR (a solid immediate release formulation of SO) and alcohol (0.7 (males) or 0.57 (females) g kg(-1) alcohol using 40% vodka). METHODS In a randomized, double-blind, double-dummy, crossover(More)
84.6 %). The biological markers normalized in both groups significantly without any group differences. Neither cognitive impairment nor adverse events were found more often in one of the groups. Interpretation. sodium oxybate and oxazepam are both effective and safe in treating alcohol withdrawal and in reducing craving for alcohol. Any kind of craving(More)
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