Philippe Gosse

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BACKGROUND Conflicting blood pressure-lowering effects of catheter-based renal artery denervation have been reported in patients with resistant hypertension. We compared the ambulatory blood pressure-lowering efficacy and safety of radiofrequency-based renal denervation added to a standardised stepped-care antihypertensive treatment (SSAHT) with the same(More)
BACKGROUND The use of ambulatory recordings of blood pressure (BP) was proposed to estimate arterial stiffness (AS). We compared the relative value of the ambulatory AS index (AASI), and of the slope of pulse pressure (PP) according to mean BP (MBP) obtained from 24-h ambulatory BP monitoring, to the monitoring of the arrival time of Korotkoff sounds (QKD(More)
REVIEW ARTICLE Assembly and secretion of hepatic very-low-density lipoprotein RESEARCH PAPERS Proteins Neoantigens in complement component C3 as detected by mono-clonal antibodies. Mapping of the recognized epitopes by synthetic peptides Myelin basic protein is affected by reduced synthesis of myelin proteolipid protein in the jimpy mouse Botulinum type F(More)
Ambulatory measurement of timing of Korotkoff sounds (QKD interval) gives an estimate of arterial distensibility derived from the velocity of the pulse wave over a vascular territory that includes the ascending aorta. The main advantages of the method are that it is entirely automatic, non-operator-dependent, and highly reproducible, and produces a measure(More)
DEFINITION AND PREVALENCE OF WHITE-COAT HYPERTENSION: White-coat hypertension describes the phenomenon of an abnormal blood pressure reading when taken by a physician and a normal reading with ambulatory or home monitoring. The results of studies suggest that the true prevalence of white-coat hypertension may be 20%. The magnitude of the effect using either(More)
BACKGROUND Ambulatory blood pressure (BP) is more sensitive than office BP and is highly correlated with the left ventricular mass (LVM) of hypertensive patients with left ventricular hypertrophy (LVH). METHODS In this prospectively designed ancillary study of the PICXEL trial, the effects of first-line combination perindopril/indapamide on ambulatory BP(More)
Several studies have established that the increase in arterial stiffness (AS) is a cardiovascular risk factor but to date no studies have evaluated in hypertensive patients its prognostic value in comparison with another powerful risk factor, left ventricular mass (LVM) as measured by echocardiography. We prospectively evaluated the prognostic value of AS(More)
Measurement of blood pressure in the clinic may provide a false impression of blood pressure control. Ambulatory blood pressure monitoring (ABPM) allows the automatic recording of the circadian variation in blood pressure and evaluation of the efficacy of antihypertensive medication throughout the dosing interval. Ambulatory blood pressure provides more(More)
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