Philippe E. Thomas

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We describe our approach for the extraction of drug-drug interactions from literature. The proposed method builds majority voting ensembles of contrasting machine learning methods, which exploit different linguistic feature spaces. We evaluated our approach in the context of the DDI Extraction 2011 challenge, where using document-wise cross-validation, the(More)
The most important way of conveying new findings in biomedical research is scientific publication. Extraction of protein-protein interactions (PPIs) reported in scientific publications is one of the core topics of text mining in the life sciences. Recently, a new class of such methods has been proposed - convolution kernels that identify PPIs using deep(More)
UNLABELLED Behavioral and psychological symptoms in dementia (BPSD) are very common, with 90% of patients experiencing at least one during the course of the disease. One-third of persons with dementia have depressive symptoms, and concomitant BPSD are very likely. OBJECTIVE This study aimed to characterize the psychological and behavioral manifestations(More)
Most relation extraction methods, especially in the domain of biology, rely on machine learning methods to classify a co-occurring pair of entities in a sentence to be related or not. Such an approach requires a training corpus, which involves expert annotation and is tedious, time-consuming, and expensive. We overcome this problem by the use of existing(More)
The extraction of protein-protein interactions (PPIs) reported in scientific publications is one of the most studied topics in Text Mining in the Life Sciences, as such algorithms can substantially decrease the effort for databases curators. The currently best methods for this task are based on analyzing the dependency tree (DT) representation of sentences.(More)
BACKGROUND Frontal lobe syndromes include reduced activity, particularly a diminution of spontaneous activity, lack of drive, inability to plan ahead, and induce a lack of concern. These last points constitute the executive dysfunction syndrome. That executive dysfunction could be the core defect in patients with geriatric or vascular depression, and might(More)
BACKGROUND The BioCreative challenge evaluation is a community-wide effort for evaluating text mining and information extraction systems applied to the biological domain. The biocurator community, as an active user of biomedical literature, provides a diverse and engaged end user group for text mining tools. Earlier BioCreative challenges involved many text(More)
BACKGROUND Alzheimer's disease and related syndromes have heavy social and human consequences for the patient and his family. Beyond the neuropsychiatric effects of specific therapies for dementia, one of today's challenges is the quality of life for both patients and their informal caregivers. OBJECTIVES This survey tends to determine parameters(More)
Research results are primarily published in scientific literature and curation efforts cannot keep up with the rapid growth of published literature. The plethora of knowledge remains hidden in large text repositories like MEDLINE. Consequently, life scientists have to spend a great amount of time searching for specific information. The enormous ambiguity(More)
CONTEXT Prospective study of the complaints, problems and requirements of the main caregiver providing home care for dementia patients. OBJECTIVES To determine the complaints of home caregivers, how they are interrelated and what causes them. RESOURCES Self-administered questionnaire of 42 questions on the patient and caregiver, including a list of(More)