Philippe De Souza

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Quinolones are antibacterial agents that have the potential to induce Achilles tendon disorders – such as tendinitis or even ruptures – in patients treated with these drugs. We studied the effects of ciprofloxacin on several proteins of Achilles tendons from immature dogs, 10- to 11-weeks-old. The dogs were treated orally for 5 days with 30 or 200 mg(More)
Circulating tumour cells (CTCs) are emerging as important prognostic markers and have potential clinical utility as tumour biomarkers for targeted cancer therapy. Although CTCs were proposed more than 100 years ago as potential precursors that may form metastatic lesions, formal evidence that CTCs are indeed capable of initiating metastases is limited.(More)
In the early design stages of embedded applications, it becomes necessary to have a very realistic simulation environment dedicated to the prototyping and to the evaluation of these Advanced Driving Assistance Systems (ADAS). This Numerical simulation stage is gradually becoming a strong advantage in active safety. The use of realistic numerical models(More)
Furthermore, the complexity of these systems in conjunction with the nearly infinite number of parameter combinations related to the usage profile of functions based on image sensors push us to think about testing optimization methods and tool standards to support the design and validation phases of ADAS systems. The resources required for the validation(More)
Table of contents INTRODUCTION ................................................................................................................................................ 1 WORKFLOW AND PROPOSED TOOLING ............................................................................................................. 2 Definition and generation of relevant(More)
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