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  • Karel de Gendt, Johannes V Swinnen, +12 authors Guido Verhoeven
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2004 (First Publication: 3 February 2004)
  • Androgens control spermatogenesis, but germ cells themselves do not express a functional androgen receptor (AR). Androgen regulation is thought to be mediated by Sertoli and peritubular myoid cells,Continue Reading
  • Catriona M. Paul, Serena Teng, Philippa T K Saunders
  • Biology, Medicine
  • Biology of reproduction
  • 2009 (First Publication: 1 May 2009)
  • Abstract Spermatogenesis is a temperature-dependent process, and increases in scrotal temperature can disrupt its progression. We previously showed that heat stress causes DNA damage in germ cells,Continue Reading
  • Michelle Anne Welsh, Philippa T K Saunders, Nina Atanassova, Richard M. Sharpe, Lee Smith
  • Biology, Medicine
  • FASEB journal : official publication of the…
  • 2009 (First Publication: 1 December 2009)
  • Androgens are essential for normal spermatogenesis and male fertility, but how androgens exert this effect remains uncertain. Androgen receptors (ARs) are expressed in several testicular cell types,Continue Reading
  • Rod T. Mitchell, Andrew J. Childs, +6 authors Richard M. Sharpe
  • Biology, Medicine
  • The Journal of clinical endocrinology and…
  • 2012 (First Publication: 1 March 2012)
  • CONTEXT Phthalates are ubiquitous environmental chemicals. Fetal exposure to certain phthalates [e.g. di-n-butyl phthalate (DBP)] causes masculinization disorders in rats, raising concern for similarContinue Reading
  • Hilary O D Critchley, Teresa A. Henderson, +4 authors Philippa T K Saunders
  • Medicine
  • The Journal of clinical endocrinology and…
  • 2002
  • Estrogen action is mediated via two subtypes of the estrogen receptor (ER), usually referred to as ERalpha and ERbeta. We have previously compared the spatial and temporal expressions of ERalpha andContinue Reading