Philippa Pearmain

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BACKGROUND Endometrial cancer is the most common gynaecological cancer in the western world, the incidence increasing in the United Kingdom by over 40% since 1993. Two types of endometrial cancer exist - oestrogen-dependent type 1 with good prognosis and non-oestrogen-dependent type 2 with poor prognosis. The histopathological distribution of the increase(More)
Introduction Neuroendocrine carcinoma (NEC) of the cervix is associated with a poor prognosis despite multimodal treatment. The correct diagnosis of this tumor type is imperative to provide clinicians and patients with prognostic information and ensure that appropriate treatment is provided. Methods A clinicopathological study was undertaken on all cervical(More)
OBJECTIVES To assess the effectiveness and cost-effectiveness of adding automated image analysis to cervical screening programmes. DATA SOURCES Searching of all major electronic databases to the end of 2000 was supplemented by a detailed survey for unpublished UK literature. METHOD Four systematic reviews were conducted according to recognised guidance.(More)
OBJECTIVE The aim of the study was to investigate the impact of country of birth on the pattern of disease and survival from cervical cancer in women living in the United Kingdom. MATERIALS AND METHODS A retrospective database evaluation study was performed to review all cases of cervical cancer diagnosed in the Pan-Birmingham Cancer Network between 2005(More)
OBJECTIVE  To monitor the effectiveness of the cervical screening programme and identify suboptimal management in order to improve patient care. DESIGN  Retrospective study. SETTING   A university hospital serving a population of 1 million people. POPULATION  All women diagnosed with a cervical cancer between 2003 and 2006. METHODS   Analysis of(More)
OBJECTIVES To examine the ability of existing classification systems to provide screening histories for invasive cervical cancers which can be used in the evaluation of the NHS Cervical Screening Programme (NHSCSP), and to provide the diagnostic route data item required for the National Cancer Data Set (NCDS). METHODS The ability of existing(More)
BACKGROUND Regional Cervical Screening Quality Assurance Reference Centres maintain and improve the quality of their local cervical screening programmes by monitoring standards based on a range of outcome measures. The classification of invasive cervical cancer screening histories can aid the interpretation of cervical cancer incidence trends in cervical(More)
AIMS Residents of one street expressed concern about the number of incident cancers, following the installation of a nearby mobile phone base station. The investigation explored whether the base station could be responsible for the cancers. METHODS Data were collected from residents' medical records. GPs and oncologists provided further information. (More)
OBJECTIVES The colposcopically directed punch biopsy has been an integral component of colposcopic practice. In light of the changing landscape of the cervical screening programme, a study was conducted to investigate the current practice of British Society of Colposcopy and Cervical Pathology-accredited colposcopists on technique and rationale for(More)
OBJECTIVE Multidisciplinary colposcopy clinicopathology correlation meetings are deemed to be an important aspect of colposcopic quality assurance and are often a focus of attention in colposcopy quality assurance peer-review assessments. Despite this, there are few data on such meetings detailing activity or providing benchmarks for audit. MATERIALS AND(More)