Philip Toozs-Hobson

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BACKGROUND Various types of suburethral tapes inserted via the transobturator route (tension-free vaginal tape obturator route [TVTO] and transobturator tape [TOT]) have been widely adopted for treatment of stress urinary incontinence (SUI) before proper evaluation of their effectiveness and complications. OBJECTIVES To assess the effectiveness and(More)
STUDY TYPE Therapy (meta-analysis) Level of Evidence 1a. OBJECTIVES To assess the effectiveness and complications of transobturator tape (inside-out and outside-in, TOT) by means of a systematic review of direct and indirect randomized controlled trials (RCTs). METHOD MEDLINE, EMBASE, CINAHL, LILIACS (up to December 2008), CENTRAL (The Cochrane Library,(More)
OBJECTIVE To compare two new generation antimuscarinics at their recommended doses for treatment of overactive bladder syndrome (OAB). METHODS A prospective, double blind, double-dummy, two-arm, parallel-group, 12-week study was conducted to compare the efficacy and safety of solifenacin 5 or 10 mg and tolterodine extended release (ER) 4 mg once daily in(More)
BACKGROUND Emerging data suggest botulinum toxin is an effective treatment for detrusor overactivity (DO), but large studies confirming efficacy and safety are lacking. OBJECTIVE Study the efficacy and safety of onabotulinumtoxinA (onaBoNTA) for the treatment of DO. DESIGN, SETTING, AND PARTICIPANTS A double-blind placebo-controlled randomised trial in(More)
OBJECTIVES To assess if mode of delivery is associated with increased symptoms of anal incontinence following childbirth. DESIGN Systematic review of all relevant studies in English. DATA SOURCES Medline, Embase, Cochrane Library, bibliographies of retrieved primary articles and consultation with experts. STUDY SELECTION AND DATA EXTRACTION Data were(More)
Sir, We congratulate Abdel Fattah et al.1 for their honesty in reporting the results of their pelvic floor surgery so candidly. However, there are a number of points that we feel need further clarification and perhaps we would suggest a different conclusion. First, the authors state that the procedures were exclusively for two indications, failed previous(More)
OBJECTIVE To determine whether transvaginal ultrasound measurement of bladder wall thickness could replace ambulatory urodynamics when investigating women with lower urinary tract dysfunction not explained by conventional laboratory urodynamic studies. DESIGN A blinded prospective study. SETTING Tertiary referral unit in a London teaching hospital. (More)
Standardized terminology has yet to be developed for reporting the outcomes for surgery for pelvic organ prolapse (POP). This report combines the input of the Terminology and Standardization Committees of the International Urogynecological Association (IUGA) and the International Continence Society (ICS) and a joint Working Group on this topic, as well as(More)
OBJECTIVES To investigate prolapse symptoms and objectively measured pelvic organ prolapse, 12 years after childbirth, and association with delivery mode history. DESIGN Twelve-year longitudinal study. SETTING Maternity units in Aberdeen, Birmingham and Dunedin. POPULATION Women dwelling in the community. METHODS Data from women were collected 12(More)