Philip Reichert

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Carbocyclic arabinofuranosyladenine (cyclaradine), a novel nucleoside analog with such desired features as hydrolytic and enzymatic stability, adenosine deaminase resistance, and low systemic toxicity, inhibited the replication of herpes simplex virus types 1 and 2. The 5'-methoxyacetate prodrug form exhibited significant efficacy in the topical treatment(More)
1. Animals immunized with the formalinized filtrates of young toxic cultures of B. botulinus produce an antitoxic serum poor in precipitins. 2. Animals immunized with the formalinized filtrates of old and partly autolyzed toxic cultures produce an antitoxic serum containing precipitins. 3. Animals immunized with toxin-free autolyzed bacteria produce a serum(More)
Rat brain cysteine sulfinate decarboxylase (EC 4.1.1.29), a key enzyme in taurine biosynthesis, has been separated from glutamate decarboxylase (EC 4.1.1.15) associated activity and purified to apparent homogeneity. The monomeric enzyme of molecular weight 70,000 +/- 2,000 exhibits half-maximal velocity with 90 +/- 40 ? M cysteine sulfinate or approximately(More)
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