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AIM To evaluate smear layer removal by different irrigating solutions under ultrasonic agitation. METHODOLOGY Twenty recently extracted mandibular incisors with a single root canal were divided into four equal groups. Three groups were instrumented using the modified double-flared technique, the fourth remained unprepared. Each group was irrigated with(More)
PURPOSE To investigate pulpal injury by measuring odontoblast numbers, and pulp dentin repair activity by measuring reactionary dentin area, in relation to the remaining dentin thickness (RDT) of cavity preparations in 217 human teeth. MATERIALS AND METHODS Cavities were restored with adhesive bonded composite, resin-modified glass-ionomer cement, zinc(More)
This study investigated the effect of direction of file oscillation on the amount of debris and smear remaining within oval canals. Sixty-five lower premolars were allocated to six experimental groups (n = 10) and one control group (n = 5). Canals were prepared using Gates Glidden burs and hand instruments. Preparations were completed using either an(More)
The effect of bismuth oxide (Bi2O3) radioopacifier addition on the material properties of an endodontic Portland cement-based system were investigated. Increasing Bi2O3 content from 0 to 10 wt % resulted in a deterioration of mechanical strength from 82 to 40 MPa, decreasing gradually on further addition to 29 MPa for 40 wt %. Bi2O3 content increase also(More)
Endosonic files are prone to constraint; this reduces their efficiency, particularly in the apical third and in curved root canals. Precurving the file may reduce constraint, thereby improving the file's ability to debride. This investigation was undertaken to compare both straight and precurved endosonic files as to debris and smear layer removal.(More)
AIM To consider the survival of root canal treatment provided within the General Dental Services in England and Wales, with failure being defined as re-treating of a root canal, apical surgery or extraction. METHODS A data set was established consisting of patients, 18 years or older, whose birthdays were included within a set of randomly selected dates(More)
Dentistry is entering an exciting era in which many of the advances in biotechnology offer opportunities for exploitation in novel and more effective therapies. Pulp healing is complex and dependent on the extent of injury, among many other factors. Many of the molecular and cellular processes involved in these healing events recapitulate developmental(More)
OBJECTIVES To analyze the soluble components of setting and set mineral trioxide aggregate (MTA), assess the abilities of two varieties of MTA and Ca(OH)(2) solutions to solubilise dentine matrix proteins (DMPs) and determine if these extracts contain signalling molecules important to pulpal repair and regeneration. METHODS The metallic ion composition of(More)
UNLABELLED The odontoblast is the secretory cell responsible for primary, secondary and tertiary reactionary dentinogenesis. We provide evidence that the changes in secretory activity of odontoblasts reflect differential transcriptional control and that common regulatory processes may exist between dentine and bone. INTRODUCTION Based on the hypothesis(More)
INTRODUCTION We have previously shown that the p38 gene is highly expressed in odontoblasts during active primary dentinogenesis, but is drastically down-regulated as cells become quiescent in secondary dentinogenesis. Based on these observations, we hypothesized that p38 expression might be upregulated, and the protein activated by phosphorylation, when(More)