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  • Philip A. Watson, Katharine Ellwood-Yen, Jennifer P King, John Wongvipat, Michelle M. LeBeau, Charles L. Sawyers
  • Biology, Medicine
  • Cancer research
  • 2005 (First Publication: 15 December 2005)
  • Insights into the molecular basis of hormone-refractory prostate cancer have principally relied on human prostate cancer cell lines, all of which were derived from patients who had already failedContinue Reading
  • Daniel L. J. Thorek, Philip A. Watson, +21 authors David Ulmert
  • Biology, Medicine
  • Science Translational Medicine
  • 2016 (First Publication: 30 November 2016)
  • Targeting the androgen receptor (AR) pathway prolongs survival in patients with prostate cancer, but resistance rapidly develops. Understanding this resistance is confounded by a lack of noninvasiveContinue Reading