Pham Manh Hung

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The percentage and absolute numbers of peripheral blood lymphocytes and EAC-rosette forming cells were evaluated in B77 tumor bearing rats. The peripheral blood lymphocytes were in high level even in rats bearing very small tumors; this result suggest the mobilization of lymphoyctes into peripheral blood in tumor bearing rats. The increase of EAC-rosette(More)
Leukocytes of peripheral blood of F1 hybrid inbred strain of rats LW X AVN and rats of inbred Lewis strain, immunized for three consecutive weeks with increasing doses of live or dead MC-1 or B 77 tumor cells, incubated for 20 hours with specific tumor extract, showed a lower adhering ability (LAI 32.8 +/- 16.6, 44.4 +/- 14.0, 43.1 +/- 7.4%) than that of(More)
Using a new modification of the tube LAI test, LAI reactivity was followed in rats of the inbred Lewis (LW) strain with transplanted syngeneic B 77 tumors before and one month after a surgical removal of the tumors. A significant decline in LAI reactivity was noted after a thorough extirpation of the tumors as compared to that prior to the surgical(More)
A modified form of the leukocyte adherence inhibition assay (LAI assay) has been used to detect the blocking factor in serum of the Lewis (LW) inbred rats and the F1 hybrids of the inbred LW X AVN strains with transplantated syngeneic B77 and MC1 tumors. This study has indicated that the cell mediated antitumor immune response of rats immunized with living(More)
To monitor the specific antitumor immunity to patients with malignant melanoma of the uveal tissue, use was made of the 20-hr modification of the leukocyte adherence inhibition (LAI) test. Simultaneously, changes in the proportionally of T (total and active) and B lymphocytes in peripheral blood were followed in the same patients by the E and EAC rosette(More)
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