Phalguni Gupta

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To understand the high variability of the asymptomatic interval between primary human immunodeficiency virus type 1 (HIV-1) infection and the development of AIDS, we studied the evolution of the C2-V5 region of the HIV-1 env gene and of T-cell subsets in nine men with a moderate or slow rate of disease progression. They were monitored from the time of(More)
The relation between viremia and clinical outcome in individuals infected with human immunodeficiency virus-type 1 (HIV-1) has important implications for therapeutic research and clinical care. HIV-1 RNA in plasma was quantified with a branched-DNA signal amplification assay as a measure of viral load in a cohort of 180 seropositive men studied for more(More)
BACKGROUND The rate of disease progression among persons infected with human immunodeficiency virus type 1 (HIV-1) varies widely, and the relative prognostic value of markers of disease activity has not been defined. OBJECTIVE To compare clinical, serologic, cellular, and virologic markers for their ability to predict progression to the acquired(More)
This paper presents an efficient approach for localization of ear from an arbitrary 2D side face image with varying background. Outer helix curves of ears moving parallel to each other are used as feature for localizing ear in an image. Using Canny edge detector, edges are extracted from the whole image. These edges are segmented in convex and concave(More)
OBJECTIVES Kaposi's sarcoma-associated herpesvirus (KSHV), a newly discovered human gammaherpesvirus, is found in the majority of KS lesions from patients with and without AIDS. Peripheral blood mononuclear cells (PBMC) were examined for KSHV DNA to determine whether viral infection precedes onset of this neoplasm. DESIGN Randomized and blinded(More)
OBJECTIVE To investigate the relation between the quantity of human immunodeficiency virus type 1 (HIV-1) RNA in plasma and the risk for the acquired immunodeficiency syndrome (AIDS) or a decline in the CD4+ T-cell count after seroconversion. DESIGN Prospective study. PATIENTS 62 homosexual men with documented HIV-1 seroconversion. SETTING University(More)
India is experiencing a rapid spread of human immunodeficiency virus type 1 (HIV-1), primarily through heterosexual transmission of subtype C viruses. To delineate the molecular features of HIV-1 circulating in India, we sequenced the V3-V4 region of viral env from 21 individuals attending an HIV clinic in Calcutta, the most populous city in the eastern(More)
This paper proposes an efficient technique for automatic localization of ear from side face images. The technique is rotation, scale and shape invariant and makes use of the connected components in a graph obtained from the edge map of the side face image. It has been evaluated on IIT Kanpur database consisting of 2672 side faces with variable sizes,(More)
Infection of T cells by HIV-1 can occur through binding of virus to dendritic cell (DC)-specific ICAM-3 grabbing nonintegrin (DC-SIGN) on dendritic cells and transfer of virus to CD4+ T cells. Here we show that a subset of B cells in the blood and tonsils of normal donors expressed DC-SIGN, and that this increased after stimulation in vitro with interleukin(More)