PhD Yoji Nagashima MD

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Pancreatic cancer is an aggressive malignancy with one of the worst mortality rates of all cancers. Recently, collapsin response mediator proteins (CRMPs) were reported to be associated with proliferation, apoptosis, differentiation, and invasion in several cancers. However, CRMP expression and their role in pancreatic cancer have not been investigated.(More)
The atypical protein kinase C lambda/iota (aPKCλ/ι) is involved in several signal transduction pathways that influence cell growth, apoptosis, and the establishment and maintenance of epithelial cell polarity. Overexpression of aPKCλ/ι has been reported in several cancers and been shown to be associated with oncogenesis. However, the expression and role of(More)
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