Peyr Olivier

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Perinatal brain injuries often result in irreversible learning disabilities, which manifest in early childhood. These injuries are chiefly ascribable to marked susceptibility of the immature brain to glutamate-induced excitotoxicity. No treatments are available. One well-characterized model of perinatal brain injuries consists in injecting the glutamate(More)
The purpose of this study was to examine the dose related effects of 6-hydroxydopamine (6-OHDA) on the electroretinographic (ERG) B-wave amplitude and on retinal concentrations of dopamine (DA) and its main metabolites homovanillic acid (HVA) and dihydroxyphenylacetic acid (DOPAC). Doses of 6-OHDA (60, 300 or 1200 micrograms) were dissolved in a 0.9 percent(More)
The absence of sensory adaptations in patients who have an esotropia of 12 to 18 degrees constitutes what has been described as the blind spot syndrome. Here, the physiological blind spot is said to provide the means of avoiding diplopia and confusion. The small size of the optic disc and variations of the angle of deviation at different positions of gaze(More)
Two series of experiments are reported on incremental increases of ischemia and monitoring of recovery from total ischemia of varying duration. In the first, rods show hyper-responses and cones do not; changes in amplitude and delays appear at higher levels of ischemia in cones than they do in rods. In the second series, cones do not recover up to control(More)
The Maddox double rod test showed subjective excyclotropia of the nonparetic eye in 15 of 60 patients with unilateral superior oblique muscle palsy. This response was reported consistently by patients who habitually fixated with the paretic eye. This phenomenon is the results of a monocular sensorial adaptation to the cyclodeviation by means of a reordering(More)
OBJECTIVES Growing evidence suggests that vitamin D plays a key role in the pathogenesis and progression of autoimmune diseases, including systemic lupus erythematosus (SLE). Recent studies have found an association between lower serum 25-hydroxyvitamin D (25(OH)D) levels and higher SLE activity. We studied the relationship between 25(OH)D levels and(More)
The aim of this study was to determine whether perfusion-scintillation scanning, used as a predictive pre-operative index of lung functionality in patients with lung cancer, is affected by the level of pulmonary blood flow (PBF). Twenty patients with primary lung cancer underwent spirometry and a radionuclide-perfusion scan (macroaggregated albumin(More)
The authors report a patient with unilateral painful hand and moving finger in whom tactile stimulation interrupted both the movement and the pain. This effect suggests a gating mechanism at a segmental level. The difference between afferent and efferent pathway levels and the delay of several months between trauma and occurrence of symptoms support a(More)
Kaposi's sarcoma (KS) has been reported in 6% of malignancies of solid organ transplant recipients. Most of the observations have been in recipients of renal allografts but, so far, KS has not been described in lung transplantation. We report a case of bronchial KS occurring in a black patient 6 months after single lung-transplantation. Skin lesions were(More)
The purpose of the present study was to evaluate the electroretinophysiological effects of streptozotocin-induced diabetes in the rat. More specifically, both B wave amplitudes and implicit times generated with various intensities of light stimulation were examined in diabetic animals adapted to either scotopic or photopic conditions. Results indicate that(More)