Petri Nokelainen

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Gene amplification using polymerase chain reaction (PCR) was carried out on DNA samples from a total of 92 normal subjects and 52 subjects with myotonic dystrophy (DM) from European and Japanese populations, to determine the copy number of the CTG repeat associated with DM for each group. In the two populations, the number of repeats on normal chromosomes(More)
This paper presents the pedagogical usability criteria for evaluating the digital learning material. Pedagogical aspects of designing or using digital learning material are much less frequently studied than technical ones. Further, there are relatively few inventories measuring subjective end-user satisfaction with the pedagogical aspects of digital(More)
Why do some adolescents respond to interpersonal conflicts vengefully, whereas others seek more positive solutions? Three studies investigated the role of implicit theories of personality in predicting violent or vengeful responses to peer conflicts among adolescents in Grades 9 and 10. They showed that a greater belief that traits are fixed (an entity(More)
A shared document-based annotation tool was presented, and its usefulness in two different real-life web-based university-level courses (adult learners, n=27 and adolescent learners, n=23) was empirically investigated. The study design embodied three data collection phases: 1) a pre test measuring self-rated motivation, learning strategies, and social(More)
Late adult onset distal myopathies usually show vacuolar degeneration as a characteristic feature in muscle pathology. In this study vacuolar degeneration was not present in 12 patients with late adult onset distal myopathy. All patients were members of a large kindred, with 26 patients showing this new form of distal leg myopathy. Additionally, a severely(More)
Many of the possibilities of Web-based education are still unexplored. It seems that novel ways of thinking about both learning and technology are needed to get beyond the limitations of the traditional classroom setting. In this paper we introduce EDUCOSM, which focusses on the possibilities of collaboration and the open-ended nature of the Web. Its main(More)
This study presents a shared document-based annotation tool, EDUCOSM. Usefulness of the system is empirically evaluated in a real-life collaborative learning context. Relationships between learner's selfrated use of learning strategies, cognitive outcomes, and completion of various tasks in the system are investigated. An empirical study (n=31) was(More)
Student-centred learning can be used in Web-courses to increase student activity, motivation and commitment. EDUCO is a system for student-centred learning, both for the learners and the teachers. Students can use EDUCO within a standard web-browser to navigate towards useful information and Web-resources gathered into the system. The key issue is that(More)
Tibial muscular dystrophy (TMD) is a recently described muscular disease first discovered in a highly consanguineous family in Finland. The pedigree also included patients whose symptoms resembled another phenotype, classical limb-girdle muscular dystrophy. Extensive linkage analysis was carried out in this complex pedigree using 157 highly polymorphic DNA(More)