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BACKGROUND Radiolocalization and selective biopsy of the sentinel node to correctly predict the status of remaining lymph nodes may provide an alternative to axillary dissection in selected breast cancer patients with clinically negative lymph nodes. STUDY DESIGN In a nonrandomized, multicenter clinical trial, gamma probe localization for lymphatic(More)
Chest physiotherapy (CPT) is a commonly used technique in mechanically ventilated critically ill patients. This study examines the hemodynamic and metabolic changes associated with CPT and measures the attenuation by two doses of intravenous fentanyl (1.5 micrograms/kg and 3.0 micrograms/kg) on these changes. Heart rate, systolic and mean blood pressures,(More)
The relative efficacies of oral verapamil, a calcium-entry blocking drug, and propranolol, a beta-adrenergic blocking drug, were compared in 12 patients who had both stable angina pectoris and mild to moderate systemic hypertension, using a placebo-controlled, double-blind, randomized crossover protocol. Compared with placebo, both propranolol and verapamil(More)
The relation between the mesorectal vessels and the mesorectal fascia needs to be clarified, as a total mesorectal excision (TME) probably derives its advantage from the fact that the visceral or mesorectal fascia can be regarded as a “tumor-tight packaging” and does not contain anatomically preformed perforations. The purpose of this investigation was to(More)
We report one patient who presented with a spontaneous bleeding complication under phenprocoumon therapy. Oral anticoagulation was initiated due to deep-vein thrombosis which was attributed to an antiphospholipid antibody syndrome. Coagulation analysis revealed a strong and selective reduction of factor IX (F IX) activity to 1%, whereas the other vitamin(More)
In a double-blind, randomized, multicenter study the antihypertensive efficacy of cilazapril 5.0 and 2.5 mg once daily vs. placebo was examined on 180 ambulatory hypertensive subjects with supine diastolic office blood pressure (OBP) > or = 95 and < or = 115 mm Hg: a 4-week, single-blind, placebo period was followed by a 4-week double-blind treatment(More)
BACKGROUND North American data are lacking on the effect of nucleos(t)ide analogues (NA) in preventing chronic hepatitis B (CHB)-related hepatocellular carcinoma (HCC). AIM To determine the incidence of HCC in NA-treated patients and compare this risk with that predicted without treatment based on the REACH-B model. METHODS In this retrospective study,(More)
The potential hazards of abrupt withdrawal of propranolol have been described in patients with angina pectoris; however, the effects of abrupt withdrawal from long-term therapy with verapamil have not previously been investigated. The comparative effects of withdrawal from long-term treatment with propranolol and verapamil were assessed in a(More)