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Tumours ferment glucose to lactate even in the presence of oxygen (aerobic glycolysis; Warburg effect). The pentose phosphate pathway (PPP) allows glucose conversion to ribose for nucleic acid synthesis and glucose degradation to lactate. The nonoxidative part of the PPP is controlled by transketolase enzyme reactions. We have detected upregulation of a(More)
Bringing communities of buyers and sellers together in the arena of electronic commerce stimulates three major potentials: the building of trust, the collection and effective use of community knowledge and the economic impacts of accumulated buying power. In this context, we introduce the concept of Virtual Communities of Transaction and review important(More)
The Journal of Computer-Mediated Communication (JCMC, ISSN 1083-6101) is a web-based, peer-reviewed scholarly journal. Its focus is social science research on computer-mediated communication via the Internet, the World Wide Web, and wireless technologies. Within that general purview, the journal is broadly interdisciplinary, publishing work by scholars in(More)
Using electronic media for interaction with customers enables enterprises to integrate customer activity and knowledge about customers resulting in a high-quality relationship thus turning buying processes more efficient. In this paper we review the basics of personalization – how it works, where it can be used (the applications) and what makes it work (the(More)
b s t r a c t The following paper presents results from a longitudinal study about the importance and use of information and communication technology (ICT) in Swiss small and medium sized companies (SMEs). In an empirical survey, 989 questionnaires were collected and analysed (return rate 17%). The results were weighted according to company size and(More)
Inspired by the perceived success of the Social Media, an increasing number of companies have started to introduce social-media-like software systems (Enterprise Collaboration Systems). In order to study the issues and challenges that such introduction projects bring about, we selected a sample of companies and conducted interviews with managers, IT experts(More)
Abstr act. Companies worldwide are faced with an increasingly volatile business environment. This leads to frequent changes in business requirements. The research described in this paper looks at the software development process for the supporting ERP System, standard software, which is generally available through specialised ERP software vendors. We argue(More)
The original reason for the research was triggered by a disappointment felt by the authors when using the Web as research tool and business medium. Many sites feature fancy graphics, well organized content, but rarely a site induces the visitor to come back on a regular basis (with exceptions of course). The electronic commerce revolution some predicted(More)