Petra S Van Nieuwenhuyzen

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RATIONALE 3,4-Methylenedioxymethamphetamine (MDMA) and methamphetamine (METH) are illicit drugs that are increasingly used in combination. The acute and long-term effects of MDMA/METH combinations are largely uncharacterised. OBJECTIVES The current study investigated the behavioural, thermal and neurotoxic effects of MDMA and METH when given alone or in(More)
OBJECTIVE To examine the possible contribution of inflammation and breakdown of the blood-brain barrier in the central nervous system (CNS) of physiologically aged rats showing cognitive decline. METHODS Young (3- to 6-month-old) and aged (24- to 30-month-old) Wistar rats were assessed by the novel object recognition test. Vascular and inflammatory(More)
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