Petra O. Nnamani

Learn More
BACKGROUND & OBJECTIVES With the current snags from the use of Artemisinin - combination therapies (ACTs) in malaria treatment in addition to fear of cross- resistance to unrelated drugs, raising the immunocompetence of individuals in malaria endemic areas by vaccination is the best approach to malaria - free world. METHODS Water - soluble cationic(More)
The present study aimed to develop low-dose liquisolid tablets of two antimalarial drugs artemether-lumefantrine (AL) from a nanostructured lipid carrier (NLC) of lumefantrine (LUM) and estimate the potential of AL as an oral delivery system in malariogenic Wistar mice. LUM-NLCs were prepared by hot homogenization using Precirol® ATO 5/Transcutol® HP and(More)
In the present work, an attempt has been made to screen Prosopis africana seed gum (PG), anionic polymer for extended release tablet formulation. Different categories of drugs (charge basis) like diclofenac sodium (DS), chlorpheniramine maleate (CPM), and ibuprofen (IB) were compacted with PG and compared with different polymers (charge basis) like xanthan(More)
Vaccination is considered to be most effective way of fighting infectious diseases like malaria etc [1]. N, N, N-trimethylchitosan (TMC) was synthesized from chito-san. Nanoparticles of the TMC were prepared in various media (milliQ water, Na 2 CO 3 (pH 10.92), Na 2 HPO 4 (pH 9.01) and alhydrogel ® beads which were characterized as adjuvant for possible(More)
  • 1