Petia Kostova

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Human endometrium is an object of extensive restructuring and remodeling during the female reproductive life and it is quite tempting to assume that these periodic changes happen with the participation of cells that should have the basic characteristics of multipotent cells. The aim of this study was to search for the presence of cells with plastic(More)
The aim of the present study was to establish the effectiveness of the conducted in Bulgaria cervical screening program for the period 1975-1996. The dynamics of the ratio invasive cancer/in situ cancer, as well as the share of the diagnosed from cytologically signalized women were analyzed. The tendency of deterioration of each of the indices was evident.(More)
The ovarian cancer represents important medico-social problem for our country due to its significant frequency (26.1%) and high mortality (9/1000) among the oncogynecological diseases. The aim of the present review was to discuss the methods--for diagnostics of the ovarian cancer trough analyzing the possibilities for their implementation as a screening in(More)
PURPOSE To study the histological findings of the uterine cervix of women in early pregnancy and to compare them to a control group of nonpregnant women. In cases with morphology compatible with human papillomavirus (HPV) infection, DNA in situ hybridization (ISH) for the types 6, 11, 16, 18, 31 and 33 was performed. PATIENTS AND METHODS The study(More)
The purpose of this work is to review the new colposcopic classification of the International Federation for Cervical Pathology and Colposcopy (IFCPC) from 2011 and the possibilities for its application in diagnostic and treatment processes and research. It fulfills the necessity for a modern and widely applicable nomenclature of the findings and it is(More)
The malignant diseases of the female genital organs present 24.7% from the all neoplastic diseases at the women and they are significant medical and social problem. In our country, the structure of the oncogynecological incidence (1999) shows, that ovarian cancer with its 17.9% takes third place, as well as it is the leading cause for death (8.4%) among the(More)
The malignancies of the uterine cervix are the most common neoplasia during pregnancy. Cancer in situ varies from 0, 11 to 0, 55% and invasive cervical cancer is found in around 0, 03% of pregnant women. The summarized data by different authors shows that the cervical cancer can be found in the wide range between 1:250 to 1:13000 pregnancies (mean 1:2000 to(More)
The aim of this review is to present the benefits and risks of the implementation of prophylactic vaccines for cervical cancer. The classical understanding of human papilloma virus (HPV) infection and its role for the cervical oncogenesis, as well as, the place of prophylactic HPV vaccines are discussed. Results concerning the effectiveness of vaccines 10(More)
The aim of the present study is to analyze the patients with endometrial cancer, treated at Gynecology Clinic of the National Oncology Hospital, Sofia according to the stage of the disease, histological type, differentiation, the peculiarities of the spreading and metastases, the therapeutic methods applied and the obtained results. For the period(More)