Peterman Pathrose

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e22129 Background: ERCC1 is a useful marker of resistance to cisplatin and its analogues. Longer survival was noted in patients with ERCC1 negative expression when treated with platinum. VEGF and its receptor-KDR previously indicated poor prognosis with high tumor cell expression. METHODS From 1998-2008, a retrospective study included 32 patients with(More)
Effect of sub chronic doses of carbosulfan exposure on humoral and cell mediated immune responses were studied in Swiss albino mice using SRBC, BSA and dinitrochlorobenzene (DNCB) as antigens. Response of humoral and cell mediated immune responses was found to be in a dose dependent pattern. However, activity of Ach E in RBC decreased in carbosulfan treated(More)
The vitamin D receptor (VDR) is known to mediate the biological actions of 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) through its ability to regulate cellular programs of gene expression. We identified VDR- and retinoid X receptor (RXR)-interacting LXXLL peptides using a mammalian two-hybrid system and examined whether these molecules could block vitamin(More)
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