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Antibody microarrays have the potential to revolutionize protein expression profiling. The intensity of specific signal produced on a feature of such an array is related to the amount of analyte that is captured from the biological mixture by the immobilized antibody (the "capture agent"). This in turn is a function of the surface density and fractional(More)
Much work has been done to compare traffic-flow models with reality; so far, this has been done separately for microscopic, as well as for fluid-dynamical, models of traffic flow. This paper compares directly the performance of both types of models to real data. The results indicate that microscopic models, on average, seem to have a tiny advantage over(More)
The paper outlines the architecture and applications of a real-time traffic information system using Floating Car Data (FCD). The proposed system uses synergies from the GPS (Global Positioning System) based fleet disposition exploiting position data of several hundred vehicles of a taxi companies in Berlin, Nuremberg and Vienna. In order to manage the(More)
A new chip-based method to identify protein-protein interactions was developed using the guanine nucleotide exchange factor GRF2 and two interacting proteins, Ras and calmodulin, as model proteins. A generic immobilization strategy for FLAG-tagged bait proteins on a protein-repellent streptavidin chip surface was implemented by presentation of an oriented(More)