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In May 1955 the Eighth World Health Assembly adopted a Global Malaria Eradication Campaign based on the widespread use of DDT against mosquitos and of antimalarial drugs to treat malaria and to eliminate the parasite in humans. As a result of the Campaign, malaria was eradicated by 1967 from all developed countries where the disease was endemic and large(More)
A quantitative light microscopic study has been carried out on the myenteric and submucosal ganglia of the stomach, duodenum, ileum, proximal colon and rectum of the guinea-pig; the enteric ganglia of the ileum were studied also in the mouse, rabbit and sheep. The area of the profiles of nerve cells, of nerve cell nuclei and of glial nuclei, and the(More)
A new method was developed to define the distribution of mast cells in normal human skin. The population density was determined in a number of zones of different depth in the dermis. Two regions of the same limb were studied systematically. Both were shown to have mast cell populations of similar size and distribution, with a maximum density immediately(More)
Neurons and glial cells of the superior cervical ganglion of sheep were investigated with morphometric methods in the light and electron microscope. The nerve cell sectional area (measured on nucleated cell profiles) ranged from 165 to 2500 microns2, which corresponds to range in cell diameter from 14 to 56 microns and a range in cell volume from 1600 to(More)
Normal rhesus monkey erythrocytes and erythrocytes infected by P. knowlesi were labelled with galactose oxidase (EC 1.1.3.9) and tritiated sodium borohydride. The glycoproteins of normal erythrocytes were not labelled unless the cells were pretreated with neuraminidase, when peaks of activity with apparent molecular weights of 170 000, 126 000, 90 000, 50(More)
The freeze fracture technique has been used to study the internal cyto-architecture of the surface membranes of the parasite and erythrocyte in Plasmodium knowlesi infections. Six fracture faces, derived from the plasma membrane and 2 pellicular membranes, have been identified at the surface of the free merozoite. The apposed leaflets of the 2 pellicular(More)