Peter Poot

  • Citations Per Year
Learn More
A vasopressin and oxytocin containing nucleus is described for the first time in the pig hypothalamus. It is located near the third ventricle, just dorsal to the suprachiasmatic nucleus, and consists of magnocellular neurons, similar to those of the supraoptic nucleus and paraventricular nucleus. Morphometric analysis of neuronal number, size, density, and(More)
Understanding the interplay of different cellular proteins and their substrates is of major interest in the postgenomic era. For this purpose, selective isolation and identification of proteins from complex biological samples is necessary and targeted isolation of enzyme families is a challenging task. Over the last years, methods like activity-based(More)
There is a variety of approaches to reduce the complexity of the proteome on the basis of functional small molecule-protein interactions such as affinity chromatography (1) or Activity Based Protein Profiling (2). Trifunctional Capture Compounds (CCs, Figure 1A) (3) are the basis for a generic approach, in which the initial equilibrium-driven interaction(More)
There is a variety of approaches to reduce the complexity of the proteome on the basis of functional small molecule-protein interactions. We describe a generic approach based on trifunctional Capture Compounds, in which the initial equilibrium-driven interaction between a small molecule probe and target proteins is irreversibly fixed upon photo-crosslinking(More)
Prolactin (PRL) was determined in plasma of fetal pigs from 40 days post coitum (d.p.c.) onwards. Values increased in the last 3 wk of the gestational period and reached 10 ng/ml at term. Immunoreactive lactotropes could be identified as early as 31 d.p.c. Lactotrope development appeared to be biphasic, with no apparent increase in cell number in the 51-75(More)
Pituitary gonadotropic development in fetal pigs has been studied immunocytochemically. From 50 days postcoitum (p.c.) until 90 days p.c. the volume density of luteinizing hormone (LH) immunoreactive cells increased from 0.12% to 0.61% of the glandular mass of the anterior part of the pituitary gland. From 90 to 100 days p.c. a steep increase to 4.5% was(More)
The early fight-inducible proteins (ELIPs) are nuclear-encoded proteins localized in the chloroplasts and related to cab (light harvesting chlorophyll alb-binffmg) gene family. Light stress controls ELIP expression at different levels, at the level of transcription and the accumulation of the protein in the thylakoid membranes. The induction of ELIP(More)
The development and distribution of the nerves in the heart of the pig was studied macroscopically and by light microscopy. Hearts were collected from 86 fetuses between 31 and 114 days of gestation (term=114 days), from 12 neonatal pigs aged 9 and 20 days and from 6 adult sows of the Dutch Landrace breed. The effect of vagotomy produced by decapitation in(More)
Nerve fibres reactive to acetyl-thiocholine, and tissues showing catecholamine fluorescence were examined in the pulmonary trunk, ductus arteriosus and aorta of 28 pig fetuses between 31 and 113 days of gestation (term=114±1 days). Eight additional fetuses, which had been decapitated in utero at 40–43 days, were also studied at ages between 51 and 114 days(More)