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PURPOSE Because varicocele is seen often in infertile men and oxidative stress has been implicated in sperm dysfunction, we assessed spermatozoal reactive oxygen species and seminal total antioxidant capacity in men with and without varicocele. MATERIALS AND METHODS Levels of reactive oxygen species and total antioxidant capacity were measured in the(More)
OBJECTIVE To evaluate seminal oxidative stress in men after vasectomy reversal and to determine whether seminal oxidative stress could predict fertility after vasectomy reversal. DESIGN Measurement of seminal reactive oxygen species (ROS) and total antioxidant capacity (TAC) in normal donors, men who were fertile after vasectomy reversal, and men who were(More)
OBJECTIVES To review a large experience with sperm cryopreservation in patients with testicular cancer and determine the effect of clinical stage and tumor histologic features on semen quality. METHODS The prefreeze and post-thaw sperm quality of 157 patients with testicular cancer was compared with that of 50 normal donors. The impact of tumor stage and(More)
OBJECTIVE To investigate whether genetic modifiers of cystic fibrosis (CF) lung disease also predispose to congenital bilateral absence of the vas deferens (CBAVD) in association with cystic fibrosis transmembrane conductance regulator (CFTR) mutations. We tested the hypothesis that polymorphisms of transforming growth factor (TGF)-β1 (rs 1982073, rs(More)
OBJECTIVE To determine the effect of female partner age on pregnancy rates after vasectomy reversal. DESIGN Retrospective review. SETTING Two academic infertility practices. PATIENT(S) Men undergoing vasectomy reversal and their partners. INTERVENTION(S) Microsurgical vasectomy reversal. MAIN OUTCOME MEASURE(S) Patency and pregnancy rates. (More)
PURPOSE We compared vasoepididymostomy to microsurgical epididymal sperm aspiration and intracytoplasmic sperm injection for treatment of epididymal obstruction secondary to vasectomy. MATERIALS AND METHODS Results in patients who underwent vasoepididymostomy for vasectomy reversal at our institution were compared to those reported previously for(More)
OBJECTIVE The objective of our study was to examine the correlation between CT-based and radionuclide renography-based measures of split renal function in a healthy population of live potential kidney donors using 3D models generated from CT angiography. MATERIALS AND METHODS The records of 173 renal donor candidates who had undergone CT and radionuclide(More)
OBJECTIVES To determine the outcomes for vasectomy reversal performed after at least 10 years of obstruction. METHODS We performed a retrospective review of three surgeons' experience with microsurgical vasectomy reversal for obstructive intervals of at least 10 years. RESULTS The overall pregnancy rate was 37%. The patency/pregnancy rate for an(More)
PURPOSE We review the outcomes after vasectomy reversal for couples with female partners 35 years old or older. MATERIALS AND METHODS A retrospective review of experience at 2 institutions was performed. Patency was defined as the presence of motile sperm. Patients with less than 6 months of followup were excluded from the patency rate analysis unless(More)
PURPOSE The use of screening computerized tomography angiography has resulted in the increased detection of incidental nephrolithiasis in potential living renal donor candidates. We reviewed current acceptance guidelines for donors with stone disease as well as data on stone related outcomes in donors with stone disease and recipients who received a kidney(More)