Peter Middleton

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This paper examines the efficiency and effectiveness of a prescriptive systems development methodology in practice. The UK Government's mandatory Structured Systems Analysis and Design Method (SSADM) was examined to determine its value to software projects. The evidence was collected from interviews with 17 project managers, discussions with participants on(More)
—This case study examines how the lean ideas behind the Toyota production system can be applied to software project management. It is a detailed investigation of the performance of a nine-person software development team employed by BBC Worldwide based in London. The data collected in 2009 involved direct observations of the development team, the kanban(More)
Langerhans cells (LC) and other antigen-presenting cells are believed to be critical in initiating graft versus host responses that influence the outcome of allogeneic hematopoietic stem cell transplantation. However, their fate in humans is poorly understood. We have sought to define the effect of conditioning regimes and graft versus host disease (GVHD)(More)