Peter Michael Goebel

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Immunoglobulin (Ig) and T cell receptor (TCR) genes are assembled during lymphocyte maturation through site-specific V(D)J recombination events. Here we show that E2A proteins act in concert with RAG1 and RAG2 to activate Ig VK1J but not Iglambda VlambdaIII-Jlambda1 rearrangement in an embryonic kidney cell line. In contrast, EBF, but not E2A, promotes(More)
Accessibility of immunoglobulin (Ig) gene segments to V(D)J recombination is highly regulated and is normally only achieved in B cell precursors. We previously showed that ectopic expression of E2A or early B cell factor (EBF) with recombination activating gene (RAG) induces rearrangement of IgH and IgL genes in nonlymphoid cells. VkappaI genes throughout(More)
This study examined the impact of financial, cultural, and family variables on the incidence of behavioral and emotional problems in a group of two- and three-year-old Latino children. The vulnerability of these children to mental health problems stems from the many challenges faced by their families, especially those associated with acculturation and(More)
1. What is the original contribution of this work? This work investigates the emphasis of anisotropic features in the chrominance channels of color images, represented in YUV space, for compression purpose. In [3], this property is stated to be important for gray-level images by means of the contourlet transform and its pyramidal directional filter bank.(More)
In this paper, a joint solution to the problem of finding appropriate abstract representations for visual polytopes is given. By using support from convex and stochastic geometry , collecting information of views from different viewpoints, perceptual grouping of 3D point-cloud image points into halfplanes with prob-abilistic robust fitting and the(More)