Learn More
BACKGROUND Directly observed treatment short course (DOTS), the global control strategy aimed at controlling tuberculosis (TB) transmission through prompt diagnosis of symptomatic smear-positive disease, has failed to prevent rising tuberculosis incidence rates in Africa brought about by the HIV epidemic. However, rising incidence does not necessarily imply(More)
  • Beauty Makamure, Jesca Mhaka, Salome Makumbirofa, Reggie Mutetwa, Lucy Mupfumi, Peter Mason +1 other
  • 2013
INTRODUCTION Limited data exist on use of the microscopic-observation drug-susceptibility (MODS) assay among persons suspected of MDR-TB living in high HIV-prevalence settings. METHODS We retrospectively reviewed available clinical and drug susceptibility data for drug-resistant TB suspects referred for culture and drug-susceptibility testing between(More)
Alert correlation systems are post-processing modules that enable intrusion analysts to find important alerts and filter false posi-tives efficiently from the output of Intrusion Detection Systems. Typically , however, these modules require high levels of human involvement in creating the system and/or maintaining it, as patterns of attacks change as often(More)
  • Ben A Lopman, Ruanne V Barnabas, J. Ties Boerma, Godwin Chawira, Kezia Gaitskell, Tara Harrop +5 others
  • 2006
BACKGROUND Vital registration and cause of death reporting is incomplete in the countries in which the HIV epidemic is most severe. A reliable tool that is independent of HIV status is needed for measuring the frequency of AIDS deaths and ultimately the impact of antiretroviral therapy on mortality. METHODS AND FINDINGS A verbal autopsy questionnaire was(More)
In this paper, we report the first empirical study and live test of the reserve price optimisation problem in the context of Real-Time Bidding (RTB) display advertising from an operational environment. A reserve price is the minimum that the auctioneer would accept from bidders in auctions, and in a second price auction it could potentially uplift the(More)
Release of transgenic insect-resistant crops creates the potential not only for the insect pest to evolve resistance but for the escape of transgenes that may confer novel or enhanced fitness-related traits through hybridization with their wild relatives. The differential response of diamondback moth (Plutella xylostella) populations in eastern and western(More)
BACKGROUND The successful cure of tuberculosis (TB) is dependent on adherence to treatment. Various factors influence adherence, however, few are easily modifiable. There are limited data regarding correlates of psychological distress and their association with non-adherence to anti-TB treatment. METHODS In a trial of a new TB test, we measured(More)
Transgenes from transgenic oilseed rape, Brassica napus (AACC genome), can introgress into populations of wild B. rapa (AA genome), but little is known about the long-term persistence of transgenes from different transformation events. For example, transgenes that are located on the crop's C chromosomes may be lost during the process of introgression. We(More)
We conducted a cross-sectional study of second line drug resistance patterns and genetic diversity of MDR-TB isolates archived at the BRTI-TB Laboratory, Harare, between January 2007 and December 2011. DSTs were performed for second line antituberculosis drugs. XDR-TB strains were defined as MDR-TB strains with resistance to either kanamycin and ofloxacin(More)