Peter M Kouw

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We aimed to determine the coverage and yield of tuberculosis contact investigation, and compliance with guidelines, and to identify opportunities for improvement. Data were extracted from records on contacts of pulmonary tuberculosis patients at the Public Health Service (Amsterdam, the Netherlands) from 2008 to 2011. Additional data were obtained from the(More)
Haemodialysis has a profound effect on fluid balance. Since fluid is initially withdrawn from the intravascular compartment, hypovolaemia is a frequent complication. A fluid shift from the overhydrated interstitium towards the intravascular compartment can counteract hypovolaemia. However, a fast decline in extracellular osmolality may cause an increase in(More)
RATIONALE The lifetime risk of tuberculosis (TB) for infected contacts is often mentioned to be 5-10%, but these estimates are based on studies conducted decades ago, and thus may not reflect current epidemiologic conditions. OBJECTIVES To estimate the risk of TB among contacts with evidence of infection and to compare this with estimates often stated in(More)
Because clinical indices of hydration state are insensitive, the estimation of correct postdialysis dry weight is still major problem. Recently, some new techniques have been introduced to assess postdialysis dry weight more accurately. The plasma concentrations of the biochemical markers atrial natriuretic peptide (ANP) and cGMP are related to(More)
The depression of immunity to various antigens in chronic uremia is a frequently encountered phenomenon. Zinc deficiency might well be an important factor in its genesis. The aim of this study was to investigate the role of zinc deficiency in this reduced immune response. Two groups of 7 patients on haemodialysis who had failed to respond with(More)
Hypotension is one of the complications frequently seen during hemodialysis. The decrease in intravascular volume caused by ultrafiltration plays an important role in its pathogenesis. A transcellular fluid shift from the extracellular to the intracellular compartment may aggravate this depletion. Continuous recording of blood volume during dialysis would(More)
Fluid accumulation in the interstitium is frequently found after cardiac surgery. In extreme this can lead to pulmonary and myocardial oedema. The origin of this accumulation is not exactly known and may be twofold. It is probably a combination of the noninfectious whole body inflammatory response and a change in Starling forces due to a decrease in colloid(More)
An on-line haematocrit measurement in extracorporeal circuits might be useful under some clinical circumstances (e.g. haemodialysis or cardiac surgery). As no such measurement exists, a device has been developed that makes it possible to detect haematocrit (Ht) continuously without a loss of blood. It is a multi-frequency system for the detection of(More)
A study was designed to explore the possibility of detecting the haematocrit of blood by means of admittance measurements. The admittance and phase angle of blood kept in a measuring cell were determined at various frequencies between 60 kHz and 24 MHz. A reliable and accurate estimation of haematocrit was obtained in two ways. First, low-frequency(More)
Impedance cardiography is based on admittance changes induced by volume changes of the intrathoracic blood vessels, but also by the longitudinal orientation of red blood cells induced by flow. An experiment was set up to separate these two phenomena and to study their frequency dependence. Admittance changes of flowing blood with variable haematocrit, of a(More)