Peter M. C. Chen

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BACKGROUND The link of the apolipoprotein (APOE) -epsilon4 allele to Alzheimer disease (AD) has led to studies investigating the role of apoE polymorphisms in Parkinson disease (PD). The authors hypothesized that any association between PD and APOE alleles and genotypes would be too small to be detected or precisely estimated by an individual(More)
OBJECTIVE To understand the relationship of apolipoprotein E (APOE) polymorphism to dementia in Parkinson disease (PD) because the APOE epsilon4 allele is linked to Alzheimer disease. DATA SOURCE We reviewed MEDLINE, BIOSIS Previews, and ISI Web of Science from January 1, 1966, to May 7, 2004, supplemented by citation analysis from retrieved articles. (More)
Aortic valve reconstruction using leaflet grafts made from autologous pericardium is an effective surgical treatment for some forms of aortic regurgitation. Despite favorable outcomes in the hands of skilled surgeons, the procedure is underutilized because of the difficulty of sizing grafts to effectively seal with the native leaflets. Difficulty is largely(More)
—Background: The link of the apolipoprotein (APOE)-ε4 allele to Alzheimer disease (AD) has led to studies investigating the role of apoE polymorphisms in Parkinson disease (PD). The authors hypothesized that any association between PD and APOE alleles and genotypes would be too small to be detected or precisely estimated by an individual case-controlled(More)
We studied the degree of arteriolar smooth muscle constriction in the spinotrapezius muscle microcirculation of spontaneously hypertensive rats and their normotensive controls, Wistar-Kyoto rats. The constriction was expressed in the form of a nondimensional tone as the difference between steady state and dilated diameter (after papaverine treatment)(More)
A digital image processing procedure has been developed for obtaining quantitative morphometric data on the microcirculatory network in the human bulbar conjunctiva. Highlights of this semi-automated approach include: 1. extraction of morphometric information that cannot be readily obtained by manual methods--length, diameter, and diffusion distributions;(More)
This paper explores the issues and the techniques of enabling multimedia applications for the thin client computing. A prototype of a video communication system based on H.323 family of ITU-T recommendations is used to demonstrate the support of multimedia applications with a terminal server and thin clients such as Windows-based terminals. The studies on(More)
In this paper, a technique for enhancing viewing capabilities of web-based clients, called the Super Plug-in Module (SPM), is proposed. By utilizing the collaborative client-server architecture, clients can view various types of documents through the help of an application server. The application server performs document transcoding operations while acts as(More)
The Ultraviolet Imaging Telescope (UIT) was flown as part of the Astro images of a variety of astronomical objects, with a 40 ′ field of view and a resolution of about 3 ′′ , were recorded on photographic film. The data recorded during the first flight are available to the astronomical community through the National Space Science Data Center (NSSDC); the(More)
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