Peter L. Perrotta

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Human platelets are anucleate blood cells that retain cytoplasmic mRNA and maintain functionally intact protein translational capabilities. We have adapted complementary techniques of microarray and serial analysis of gene expression (SAGE) for genetic profiling of highly purified human blood platelets. Microarray analysis using the Affymetrix HG-U95Av2(More)
Information about subscriptions and ASH membership may be found online at:. ABSTRACT Platelets play critical roles in diverse hemostatic and pathologic disorders, and are broadly implicated in various biological processes that include inflammation, wound healing and thrombosis. Recent progress in high-throughput mRNA and protein profiling techniques has(More)
Infusion of hematopoietic progenitor cells following high-dose chemotherapy is frequently used to treat patients with hematological malignancies and solid tumors. We have developed a comprehensive software system to monitor these patients once they are entered into an experimental protocol. The captured data encompasses all phases of progenitor cell therapy(More)
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