Peter Kristúfek

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STUDY OBJECTIVE To compare the efficacy, tolerability, and safety of therapy with formoterol and oral slow-release theophylline (THEO) in patients with COPD. DESIGN A randomized, parallel-group study, with double-blind arms for formoterol and placebo (PL) and an open arm for oral slow-release THEO administered in individual doses on the basis of plasma(More)
BACKGROUND/AIMS Between 1996 and 1998 we investigated the occurrence of lung disorders in 82 patients with inflammatory bowel disease (30 patients with ulcerative colitis and 52 patients with Crohn's disease) and a control group of 60 subjects. The aim of our study was to determine the occurrence of pulmonary complications in patients with inflammatory(More)
The association of SLE with tuberculosis (TB) was studied in a group of 388 patients with SLE monitored between 1953-1994. TB was diagnosed in 14 patients (3.6%). The occurrence of septic fevers in SLE patients that did not respond to glucocorticoid therapy indicated the possibility of complication with TB. SLE-associated TB included miliary and(More)
We present new lung function reference values based on an investigation of 1024 healthy subjects aged 6-81 years. The dependent variables, i.e. VC, FEV1, RV, FRC, TLC, PEF, MEF50 and MEF25 are expressed as transcendent functions of age, body height and mass. A single equation covers the age range from 6 to 81 years and reflects certain phenomena such as(More)
PURPOSE The long-acting inhaled anticholinergic agent, tiotropium, is recommended as first-line maintenance therapy for moderate to very severe Chronic Obstructive Pulmonary Disease (COPD) to improve symptoms, exercise tolerance, health status, and to reduce exacerbations. Few studies have evaluated the therapeutic efficacy of tiotropium in patients in(More)
The first mycobacterioses caused by M. xenopi in Slovakia were discovered in the year 1979. Gradually they became the most often occurring mycobacterioses caused by facultative pathogenic mycobacteria. The purpose of investigation is to describe epidemiological situation of diseases caused by M. xenopi in Slovakia and to confront it with the situation in(More)
Continuing medical education (CME) is an important part of the medical practice today. After the pregraduate and postgraduate education each general practitioner and specialist should follow the CME to maintain, develop or increase the knowledge and professional skills. In May of 2004 a Slovak accreditation council for continuing medical education (SACCME)(More)