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A typical diffraction experiment will generate many images and data sets from different crystals in a very short time. This creates a challenge for the high-throughput operation of modern synchrotron beamlines as well as for the subsequent data processing. Novice users in particular may feel overwhelmed by the tables, plots and numbers that the different(More)
Maximum-likelihood X-ray macromolecular structure refinement in BUSTER has been extended with restraints facilitating the exploitation of structural similarity. The similarity can be between two or more chains within the structure being refined, thus favouring NCS, or to a distinct 'target' structure that remains fixed during refinement. The local(More)
Epidemiological studies of traffic-related air pollution typically estimate exposures at residential locations only; however, if study subjects spend time away from home, exposure measurement error, and therefore bias, may be introduced into epidemiological analyses. For two study areas (Vancouver, British Columbia, and Southern California), we use paired(More)
The consistent end-to-end simulation of airborne and spaceborne earth remote sensing systems is an important task and sometimes the only way for the adaptation and optimization of a sensor and its observation conditions, the choice and test of algorithms for data processing, error estimation and the evaluation of the capabilities of the whole sensor system.(More)
BACKGROUND EDTA-dependent pseudothrombocytopenia (EDTA-PTCP) is a common laboratory phenomenon with a prevalence ranging from 0.1-2% in hospitalized patients to 15-17% in outpatients evaluated for isolated thrombocytopenia. Despite its harmlessness, EDTA-PTCP frequently leads to time-consuming, costly and even invasive diagnostic investigations. EDTA-PTCP(More)
Large and quickly growing SAP systems? The need to test and validate in-house developments? The challenge to scramble sensitive data? Multiple parallel IT projects? Demand to simulate new business scenarios? Interfaces need to be changed or closed Users need to be set up or changed Authorizations need to be adjusted Saved objects need to be copied back(More)
Participatory Geographic Information and Multimedia Systems (PGIMSs) were developed and used by two rural communities in Indonesia. This paper reports on the empowerment impacts that resulted from this development project. Empowerment related to PGIMS is examined using a two-dimensional analytical framework that explores the phenomenon at two social scales(More)