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Antibodies specific for human T-cell leukemia-lymphoma virus type I (HTLV-I) were demonstrated in serum samples from various groups of people in South Africa, Uganda, Ghana, Nigeria, Tunisia, and Egypt. The samples had been collected for other purposes and were presumably selected without bias toward clinical conditions associated with HTLV infections.(More)
Huntington's disease (HD) is a progressive neurological disorder characterised by motor impairments caused by degeneration in the striatum. The mechanism by which the HD mutation leads to the neurodegenerative pathology of HD is still unknown. Recently it was shown that, in HD patients, early pathological changes in white matter precede selective cell death(More)
The uraemic syndrome is a complex condition that results from the retention of "waste" compounds that normally would be excreted into the urine or catabolized by the kidneys. In addition, inflammation has been implicated in symptoms associated with uraemia, including its role in the malnutrition-inflammation-atherosclerosis syndrome. Regarding vascular(More)
  • Alfano C, Magrinelli E, +43 authors Van
  • 2015
Gene therapy enhances chemotherapy tolerance and efficacy in glioblastoma patients. A high-content assay strategy for the identification and profiling of ABCG2 modulators in live cells. Assay and drug development technologies. Patient-specific metrics of invasiveness reveal significant prognostic benefit of resection in a predictable subset of gliomas. T.(More)
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